Late Break Clinical Trial Abstracts

Late Breaking Abstracts

The Effect of Probiotics on Late-Onset Sepsis in Very Preterm Infants: A Randomized Clinical Trial

Background Late onset sepsis is a frequent complication of prematurity, associated with increased mortality and morbidity. Probiotics may prevent late onset sepsis in premature infants. The aim of this study was to determine prophylactic effect of oral probiotics in prevention of late onset sepsis of very preterm infants. Materials and Methods This study was a randomized, double blinded, placeb...

Influenza antivirals currently in late‐phase clinical trial

Influenza antiviral drugs are important for the control of influenza, most specifically for the treatment of influenza patients with severe disease following infection with a seasonal influenza virus, a newly emerging influenza strain, or in the event of a pandemic. Many influenza antivirals that are currently under investigation in late-stage clinical trials differ in their mechanism of action...

Late-breaking Abstracts Presented at Scientific Sessions Aaaai Annual Meeting

Dr Caroline Roduit, Dr Remo Frei, Dr Ruth Ferstl, Susanne Loeliger, Prof. Charlotte Braun-Fahrl€ander, Prof. Erika Von Mutius, MD, MSc, Prof. Juha Pekkanen, MD, Prof. Jean-Charles Dalphin, Prof. Josef Riedler, Prof. Roger Lauener, MD, Dr Liam O’Mahony, PhD; University children’s hospital Zurich, Switzerland, Swiss Institute of Allergy and Asthma Research, Davos, Switzerland, Swiss Tropical and ...

Top-Level MeSH Disease Terms Are Not Linearly Separable in Clinical Trial Abstracts

Assessments of the efficacy and safety of medical interventions are based on systematic reviews of clinical trials. Systematic reviewing requires the screening of vast amounts of publications, which is currently done by hand. In some cases systematic reviewers reduce thousands of publications to only a handful. Whereby, they maximize sensitivity and sacrifice specificity. To reduce the number o...